WebbWe assayed the transcriptomes of 32,531 individual nuclei extracted from the nucleus accumbens (NAc) of nine donors with AUD and nine controls. Our study identified 17 clearly delineated cell types. We detected 26 transcriptome‐wide significant association signals (q‐value <0.1) that mainly involved medium spiny neurons with both D1‐type and … Webb4 feb. 2014 · And much recent research supports this notion that impaired integration in the brain is at the root of many psychiatric disturbances. And so adolescent remodeling …
Mechanism of demyelination and remyelination in multiple …
WebbMyelination is a finely regulated process that involves interactions between oligodendrocytes, axons, astrocytes and microglia. Hypomyelinating leukodystrophies … Webb20 nov. 2015 · A process promoting learning by maintaining myelin integrity is not incompatible with a process of myelination promoting learning specifically. Mice in the running-wheel study were relatively ... porthaven care group
(PDF) Schwann cell O-GlcNAcylation promotes peripheral nerve ...
WebbA prominent feature of demyelinating diseases such as multiple sclerosis (MS) is the degeneration and loss of previously established functional myelin sheaths, which results in impaired signal propagation and axonal damage. However, at least in early disease stages, partial replacement of lost oligodendrocytes and thus remyelination occur as a result of … Webb11 feb. 2024 · Chan added, “We are now seeing that the process of oligodendrocyte generation and myelination can be quite dynamic in the normal adult brain. It’s a form of … porthaven care home ledbury