Webdently derived embryonal carcinomas, OTF9-63 and C86SJA1 (Fig. 4c ), but not in mouse L-cell fibroblasts or L8 myoblasts (data not shown). We also fused hprt-OTF9-63 cells with … WebIn this study we evaluate, for the first time, the molecular mechanism that underlies the extinction of a tissue-specific transcription factor, Oct-3/4, in somatic cell hybrids and compared it with its down-regulation in retinoic acid (RA)-treated embryonal carcinoma (EC) cells. The Oct-3/4 gene, which belongs to the POU family of transcription factors and is …
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