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Tau Does Not Stabilize Axonal Microtubules but Rather
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Web01. apr 2024. · First, MAP6 has been thought to be a structural MAP and thus to bind to the exterior of the microtubule lattice. Second, although intraluminal particles have been … Web09. jul 2024. · When MAP6 is depleted, the labile microtubule mass becomes even more labile, indicating that, unlike tau, MAP6 is a genuine stabilizer of axonal microtubules. We conclude that tau is not a stabilizer of axonal microtubules but is enriched on the labile domain of the microtubule to promote its assembly while limiting the binding to it of … gillyfest sheffield 2022