WebCREB was first described in 1987 as a cAMP-responsive transcription factor regulating the somatostatin gene. Genes whose transcription is regulated by CREB include: c-fos, the … WebJul 3, 2024 · The P38/CREB/MMP13 axis is active in osteoarthritic chondrocytes and may cause the degeneration of cartilage. Effective new therapy directed against this pathway could be developed. ... Phosphorylated (p)-P38, p-CREB, and MMP13 were evaluated by Western blot analysis. Anisomycin was used to activate P38, and p-P38, p-CREB, and …
Activation of the P38/CREB/MMP13 axis is associated with ... - PubMed
WebOct 11, 2024 · Total and phosphorylated CREB expression in lung and PASMCs. a Lung tissues were isolated from control and rats induced by MCT for 1, 2, 3 and 4 weeks. n=5. b PASMCs were isolated from control and rats induced by MCT for 1, 2, 3 and 4 weeks. n=7. c Total and phosphorylated CREB expression in hypoxia+su5416-induced PH. WebOur CREB polyclonal, recombinant monoclonal, monoclonal and recombinant polyclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been … human composting machine
CREB activity modulates neural cell proliferation, …
WebMar 7, 2005 · Using CREB:DNA complexes obtained from HEK293T cells by ChIP to screen the Hu19K array ( P ≤ 0.001, binding ratio ≥2), we found ≈3,000 CREB-positive promoters, accounting for nearly 20% of protein coding genes (2,811/16,361 or 17%; see Table 6, which is published as supporting information on the PNAS web site, and … WebMonoclonal Antibody for studying CREB (Ser133) phosphate. Cited in 6 publications. Validated for Western Blotting. Highly specific and rigorously validated in-house, Phospho-CREB (Ser133) (87G3) Rabbit Monoclonal Antibody (Biotinylated) (CST #4095) is ready to ship. ... For western blots, incubate membrane with diluted primary antibody in 5% w ... WebDec 1, 2024 · To investigate the role of CREB in Sb-induced neuronal apoptosis, we evaluated CREB phosphorylation levels by immunoblotting after treating PC12 cells with 0, 25, 50, and 75 μM Sb for 24 h. Sb treatment increased the levels of CREB phosphorylation in a dose-dependent manner; the total CREB levels were not affected by Sb treatment ( … holistic pet care oakland