WebJul 2, 2024 · Taken together, our results suggested that the natural product kayadiol exerted anticancer effects through p53-mediated ferroptosis in NK/T cell lymphoma cells. Hence, it can serve as an effective alternative in the treatment of NK/T cell lymphoma, especially for patients exhibiting chemoresistance. Peer Review reports Introduction WebMar 22, 2024 · Cisplatin was used to induce apoptosis of CT26 and MC38 cells. After the tumor cells grew to 60%–70% confluence, they were treated with 0, 15, or 45 μM cisplatin for 48 h. For confirmation of apoptosis, tumor cells were stained with the annexin V-FITC/PI apoptosis detection kit (40302ES60, YEASEN).
STUB1-SMYD2 Axis Regulated Drug Resistance in Glioma cells
WebAug 1, 2024 · In this study, we demonstrated that Salvianolic acid B (SalB), one of the major ingredients of Salvia miltiorriza elicited vascular normalization in the mouse models of breast cancer, contributing to improved delivery and response of chemotherapeutic agent cisplatin as well as attenuated metastasis. WebApr 16, 2024 · Cisplatin (HY-17394) was purchased from MedChem Express. All other kits and reagents were purchased from the Beyotime Institute of Biotechnology (Shanghai, China). 2.2. Cell culture and transfection The A549 and A549/DDP NSCLC cells were purchased from Procell Life Science & Technology Co, Ltd. how to screenshot explorer
Cisplatin-induced pyroptosis is mediated via the CAPN1
WebOct 1, 2024 · Cisplatin caused dramatic decreases in the progression of S47 tumors by activating the p53/PIN1 axis to drive the mitochondrial cell death program. These findings serve as important proof of principle that chemotherapy can be tailored to p53 genotype. WebPDF 0.29 MB PAI-1 (Plasminogen activator inhibitor-1, also known as SERPINE1) is a member of serine protease inhibitor (SERPIN) family that acts as the primary inhibitor of two main mammalian plasminogen activators, urinary-type (uPA) and tissue-type (tPA). WebData Sheet SDS COA Handling Instructions NecroIr1 is an iridium (III) complex, serves as necroptosis inducers in Cisplatin (HY-17394)-resistant lung cancer cells (A549R). NecroIr1 selectively accumulates in … how to screenshot facebook